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BD-2 Protein, Mouse
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BD-2 Protein, Mouse

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品牌: UA BIOSCIENCE
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分子量:

5 kDa (Reducing)

纯度:
>95% by SDS-PAGE.
产品介绍
产品介绍
产品信息
荧光素标记
氨基酸序列

Ala21-Lys71

分子量

5 kDa (Reducing)

生物活性
EC50 = 0.8-1.0 ng/ml
纯度
>95% by SDS-PAGE.
内毒素水平
<0.1EU/μg
性状
Lyophilized Powder
表达系统
E.coli
缓冲体系
PBS, pH7.4
标签
No Tag
种属
Mouse
电泳JSON
[{"imgUrl":"https://univ-pmc.oss-cn-shanghai.aliyuncs.com/7c241909-045f-49c2-b71a-2307980de4e3","description":"

2μg (R: reducing condition, N: non-reducing condition).

"}]
背景
别名
Beta-defensin 2; BD-2; mBD-2; Defensin, beta 2;
背景

Beta-defensin 2 is a key component of the innate immune system, known for its antimicrobial properties and immunomodulatory functions. It is produced by various epithelial cells in response to microbial infections and plays a crucial role in host defense against pathogens. Beta-defensin 2 exhibits potent antimicrobial activity against a wide range of microorganisms, including bacteria, fungi, and viruses, by disrupting their cell membranes. In addition to its direct antimicrobial effects, beta-defensin 2 also functions as a chemoattractant for immune cells, such as neutrophils, monocytes, and dendritic cells, promoting their recruitment to sites of infection. Furthermore, beta-defensin 2 can modulate inflammatory responses by regulating cytokine production and promoting wound healing.

制备和贮存
溶解方法

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

保存方式

·12 months from date of receipt, -20 to -70 °C as supplied.
·1 month, 2 to 8 °C under sterile conditions after reconstitution.
·Please avoid repeated freeze-thaw cycles.

文献
文献

Science. 2002 Nov 1;298(5595):1025-9.

数据库链接
Accession

参考图片

2μg (R: reducing condition, N: non-reducing condition).

Measured by its binding ability in a functional ELISA. When Anti-BD-2 Recombinant Antibody is immobilized 0.5µg/mL (100µL/well), Recombinant Mouse BD-2 binds with an EC50 of 0.8-1.0ng/ml.

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货号:
UA040327-1mg
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