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BI-671800
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产品介绍
产品介绍
产品信息
商品描述
BI-671800 is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2), with IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2 transfected cells, respectively. BI-671800 has potential for the treatment of poorly controlled asthma.
分子量
501.50
纯度
98%
可溶性
DMSO : 135 mg/mL (269.19 mM; Need ultrasonic)
In vitro(体外研究)
BI-671800 (compound A) exhibits low nM potency as an antagonist of human or mouse CRTH2 in transfected cells.
In vivo(体内研究)
BI-671800 (compound A) exhibits low nM potency as an antagonist of human or mouse CRTH2 in transfected cells.
背景
分子式
C25H26F3N5O3
CAS号
1093108-50-9
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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