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Biotinylated Anti-CTLA4 antibody (DM50), Rabbit mAb

产品介绍
产品介绍
产品信息
纯化方式
Purified from cell culture supernatant by affinity chromatography

抗原名称
Cytotoxic T-lymphocyte protein 4

免疫原
Recombinant human CTLA4(Gln36-Ser161) produced by using human HEK293 cells

商品描述
Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.

克隆号
DM50

形式
Liquid. 50% Glycerol; PBS, pH7.4; 0.1% BSA. 0.1% Procline 300

产品类型
Monoclonal

应用
实验应用
ELISA (EIA), Flow Cytometry (FC/FACS)

反应种属
Human

背景
别名
CTLA4; CD152

制备和贮存
保存方式
Store at -20 degree C for 12 months (Avoid repeated freezing and thawing)
数据库链接
NCBI
1493

UniProt ID
P16410
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