Biotinylated Anti-GITR antibody (DM79), Rabbit mAb

Purified from cell culture supernatant by affinity chromatography

glucocorticoid-induced TNFR-related protein

Recombinant human GITR (Gln266-Pro162) produced by using human HEK293 cells

This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

DM79

Liquid. 50% Glycerol; PBS, pH7.4; 0.1% BSA. 0.1% Procline 300

Monoclonal

ELISA (EIA), Flow Cytometry (FC/FACS)

Human

AITR; GITR; TNFRSF18; CD357

8784

Q9Y5U5 [Other Products]