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产品介绍
产品介绍
产品信息
商品描述
BML-267 is a potent and selective PTP1B (protein tyrosine phosphatase 1B) inhibitor (IC50=11 μM)1. A similar N-des-methyl analog has been reported and has been used to probe the mechanism of PTP1B-mediated inhibition of leptin signaling. BML-267 have limited cell permeability. A cell permeable diethyl ester prodrug of BML-267 compound is available.
分子量
398.31
纯度
≥95%
可溶性
Soluble in: DMSO 10 mg/mL
IC50
protein tyrosine phosphatase 1B (PTP1B): IC50 = 11 µM
应用
实验应用
A potent and selective protein tyrosine phosphatase 1B (PTP1B) inhibitor
背景
别名
6-Methyl-2-(oxalylamino)-4,5,6,7-tetrahydrothieno[2, 3-c]pyridine-3-carboxylic acid trifluoroacetic acid salt
分子式
C11H12N2O5S•C2HF3O2
制备和贮存
保存方式
Store at -20° C
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