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产品介绍
产品信息
商品描述
Nuclear retinoic acid receptors (RARs) are transcriptional regulators with roles in cell proliferation and differentiation.1,2 BMS 493 is a pan-RAR inverse agonist that blocks RARα activity with an IC50 value of 114 nM.3,4 In all RAR types (RARα, RARβ, and RARγ), BMS493 prevents the recruitment of transcriptional coactivators to RARs while stabilizing corepressor interactions.5,6 BMS 493 has been used to elucidate the critical roles of RARs in development and immune response.3,7,8,9
分子量
404.5
纯度
≥98%
背景
分子式
C29H24O2
CAS号
215030-90-3
制备和贮存
保存方式
Store at -20℃
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