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BTN2A1 (Butyrophilin Subfamily 2 Member A1, BT2.1, BTF1)
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产品介绍
产品介绍
产品信息
纯化方式
Affinity Purified
Purified by Protein A affinity chromatography.
抗原名称
butyrophilin subfamily 2 member A1 isoform 4
免疫原
Full length recombinant corresponding to aa1-335 from human BTN2A1 (AAH16661) with GST tag. MW of the GST tag alone is 26kD.
商品描述
The MHC-encoded butyrophilin, BTN2A1, is a cell surface glycoprotein related to the extended family of B7 costimulatory molecules. BTN2A1 mRNA is expressed in most human tissues, but protein expression is significantly lower in leukocytes. The protein is an integral plasma membrane B box protein involved in lipid, fatty-acid and sterol metabolism. Recent studies reveal that the protein can negatively regulate T cell proliferation and cytokine production. Additionally, genetic studies have described polymorphisms in the protein which are reported to be associated with disorders such as sarcoidosis, myositis andulcerative colitis. Human BTN2A1 gene is located in 6p22.1.
克隆号
3A1
形式
Supplied as a liquid in PBS, pH 7.2.
产品类型
Monoclonal
应用
实验应用
ELISA (EL/EIA)
反应种属
Human
背景
别名
Anti -BTN2A1 (Butyrophilin Subfamily 2 Member A1, BT2.1, BTF1)
制备和贮存
保存方式
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
数据库链接
NCBI
11120
UniProt ID
Q7KYR7
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