C 646 (10 mg)

445.42

Selective p300/CREB-binding protein (CBP) inhibitor (K_i = 400 nM). Selective against six other histone acetyltransferases (HATs). Suppresses histone H3 and H4 acetylation in mouse fibroblast cell lines.

>98 %

Soluble to 25 mM in DMSO

4-[4-[[5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl]benzoic acid

C₂₄H₁₉N₃O6