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C-Fos is the product of an immediate early gene. It is a major nuclear target for signal transduction pathways involved in the regulation of cell grow
C-Fos is the product of an immediate early gene. It is a major nuclear target for signal transduction pathways involved in the regulation of cell grow
品牌： Usbiological
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咨询纯度：
Purified by immunoaffinity chromatography.
反应种属：
Rabbit
产品介绍
产品介绍
产品信息
抗原来源
Human
宿主
Rabbit
免疫原
Synthetic peptide corresponding to human FOS/c-FOS.
产品用途
Suitable for use in ELISA, Western Blot, Immunohistochemistry. Other applications not tested.
简单描述
C-Fos is the product of an immediate early gene. It is a major nuclear target for signal transduction pathways involved in the regulation of cell growth, differentiation, and transformation. The Fos and Jun proteins from dimeric complexes that stimulate transcription of genes containing AP-1 regulatory elements. Studies in rodents have shown that c-Fos is essential in regulating neuronal cell survival versus death. c-Fos is induced by neuronal activity, regulates the expression of the kainic acid receptor GLUR6 and brain derived neurotrophic factor (BDNF).
同种型
IgG
克隆类别
Polyclonal
纯度
Purified by immunoaffinity chromatography.
形式
Supplied as a liquid in PBS, (without Mg2+, Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
应用
实验应用
E IHC WB
推荐用量
ELISA: 1:5000 Western Blot: 1:500-1:1000 Immunohistochemistry (Paraffin): 5ug/ml Optimal dilutions to be determined by the researcher.
反应种属
Rabbit
交叉反应性
Hu Mo Rt
目标/特异性
Recognizes human FOS/c-FOS. Species Crossreactivity: Mouse, rat.
稀释度
ELISA: 1:5000 Western Blot: 1:500-1:1000 Immunohistochemistry (Paraffin): 5ug/ml Optimal dilutions to be determined by the researcher.
制备和贮存
保存方式
Storage_Temp:-20°C
Storage_and_Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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