c-IAP2 (Ac-71)

鼠

抗-c-IAP2 抗体 Ac-71 是小鼠单克隆 IgG1 κ，c-IAP2抗体, 在4篇文献中引用，规格为50 µl ascitesraised against a recombinant protein corresponding to c-IAP2 of human originEndoplasmic Reticulum Staining目前，我们还没有完成c-IAP2 抗体 (Ac-71)的首选二抗检测试剂的鉴定。这项工作正在进行中。 查看产品引用文献(4) c-IAP2 Antibody (Ac-71) is a high quality monoclonal c-IAP2 antibody (also designated BIRC3 antibody, cellular inhibitor of apoptosis 2 antibody, or cIAP2 antibody) suitable for the detection of the c-IAP2 protein of human origin. c-IAP2 Antibody (Ac-71) is available as the non-conjugated anti-c-IAP2 antibody. The baculovirus protein p35 inhibits virally induced apoptosis of invertebrate and mammalian cells and may function to impair the clearing of virally infected cells by the immune system of the host. This is accomplished at least in part by the ability of p35 to block both TNF- and FAS-mediated apoptosis through the inhibition of the ICE family of serine proteases. Three mammalian homologs of baculovirus p35, designated MIHA (mammalian IAP homolog A), MIHB and MIHC have been described. These three mammalian inhibitor of apoptosis proteins (IAPs) are designated XIAP, c-IAP1 and c-IAP2, respectively. XIAP, c-IAP1 and c-IAP2 share an N-terminal baculovirus IAP repeat (BIR) motif and a C-terminal RING finger. Although c-IAP1 and c-IAP2 do not directly associate with the TNF receptor (TNF-R), they efficiently block TNF-mediated apoptosis through their interaction with the downstream TNF-R effectors, TRAF1 and TRAF2. The interaction between the TRAF1/TRAF2 heterocomplexes and c-IAPs is dependent on a functional BIR motif.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

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干冰

HumanBIRC3

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