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IGF2R (FITC)
IGF2R (FITC)
品牌： Usbiological
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对比
咨询纯度：
Purified by Protein G affinity chromatography.
反应种属：
Rabbit
产品介绍
产品介绍
产品信息
荧光素标记
抗原来源
Human
宿主
Rabbit
免疫原
Recombinant protein corresponding to aa2328-2491 from human cation-independent mannose-6-phosphate receptor protein.
产品用途
Suitable for use in FLISA. Other applications not tested.
简单描述
Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.
同种型
IgG
克隆类别
Polyclonal
纯度
Purified by Protein G affinity chromatography.
形式
Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol. Labeled with Fluorescein isothiocyanate (FITC).
应用
实验应用
FLISA
推荐用量
Optimal dilutions to be determined by the researcher.
反应种属
Rabbit
交叉反应性
Hu
目标/特异性
Recognizes human IGF2R.
稀释度
Optimal dilutions to be determined by the researcher.
背景
别名
Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor) (CI-MPR) (M6PR) (300kD mannose 6-phosphate receptor) (MPR 300) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (CD antigen CD222), IGF2R, MPRI
制备和贮存
保存方式
Storage_Temp:-20°C
Storage_and_Stability:Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
数据库链接
UniProt ID
P11717
SwissProt
P11717
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