Candesartan (10 mg)

2541

AT₁ antagonist

440.45

2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid

Angiotensin II receptor 1 (AT₁) antagonist (IC₅₀ values are 1.12 and 2.86 nM in bovine adrenal cortex and rabbit aorta, respectively). Exhibits antihypertensive effects in animal models. Also available as a prodrug, candesartan cilexetil (Cat. No. 4792).

≥98% (HPLC)

Soluble to 100 mM in DMSO and to 10 mM in ethanol with gentle warming

CV 11974

CCOC1=NC(C=CC=C5C(O)=O)=C5N1CC2=CC=C(C3=CC=CC=C3C4=NN=NN4)C=C2

C₂₄H₂₀N₆O₃

139481-59-7