Cardiotin (SR-3)

mouse

Cardiotin抗体(SR-3)是小鼠单克隆IgM (kappa轻链)，规格为200 µg/ml 免疫human物种的Cardiotin 推荐用于 human 和 porcine 来源的Cardiotin WB, IP 和 IF检测 目前，我们还没有完成Cardiotin 抗体 (SR-3)的首选二抗检测试剂的鉴定。这项工作正在进行中。 Cardiotin is a high molecular weight protein complex located in the mitochondrial membrane. The Cardiotin structure exists as two subunits, both of which contain the same N-terminal 14 amino acid sequence, showing high homology to human skeletal muscle α-actinin. This suggests that the tetrameric configuration of the Cardiotin protein structure is a transmembrane complex with the N-terminus at the cytoplasmic side of the membrane, able to interact with Actin. During cardiac contractile dysfunction, Cardiotin distribution is affected in pathological cardiomyocytes, such as chronic ischemic myocardium. The Cardiotin monoclonal antibody can be used in immunohistochemistry for the detection of a disturbed mitochondrial activity in cardiomyocytes, such as during chronic ischemia or chronic atrial fibrillation.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

IGM-免疫球蛋白M型抗体

WB, IP, IF