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Ala24-Ser94
10 kDa (Reducing)
2μg (R: reducing condition, N: non-reducing condition).
CCL17, also known as thymus and activation-regulated chemokine (TARC), is a small cytokine belonging to the CC chemokine family. It is produced by various cell types, including dendritic cells, macrophages, and endothelial cells, and plays a crucial role in regulating immune cell migration and activation. CCL17/TARC is involved in the recruitment of T cells, particularly T helper type 2 (Th2) cells, to sites of inflammation and is implicated in the pathogenesis of allergic and inflammatory diseases, such as atopic dermatitis and asthma. CCL17/TARC binds to its receptor CCR4 and mediates chemotaxis of CCR4-expressing cells, contributing to the orchestration of immune responses.
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
·12 months from date of receipt, -20 to -70 °C as supplied.
·1 month, 2 to 8 °C under sterile conditions after reconstitution.
·Please avoid repeated freeze-thaw cycles.
Int Immunol. 1999 Jan;11(1):81-8.
参考图片
2μg (R: reducing condition, N: non-reducing condition).
>95% as determined by RP-HPLC.