CCL17/TARC Protein, Human

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CCL17/TARC Protein, Human

品牌： UA BIOSCIENCE

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参数

分子量：

10 kDa (Reducing)

纯度：

>95% by SDS-PAGE and HPLC.

产品介绍

产品信息

耦联标记

Unconjugated

氨基酸序列

Ala24-Ser94

分子量

10 kDa (Reducing)

生物活性

Test in progress.

纯度

>95% by SDS-PAGE and HPLC.

内毒素水平

<0.1EU/μg

性状

Lyophilized Powder

表达系统

E.coli

缓冲体系

20mM PB, 500mM NaCl, pH7.4

标签

No Tag

种属

Human

电泳JSON

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2μg (R: reducing condition, N: non-reducing condition).

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背景

别名

C-C motif chemokine 17; CC chemokine TARC; Small-inducible cytokine A17; Thymus and activation-regulated chemokine;

背景

CCL17, also known as thymus and activation-regulated chemokine (TARC), is a small cytokine belonging to the CC chemokine family. It is produced by various cell types, including dendritic cells, macrophages, and endothelial cells, and plays a crucial role in regulating immune cell migration and activation. CCL17/TARC is involved in the recruitment of T cells, particularly T helper type 2 (Th2) cells, to sites of inflammation and is implicated in the pathogenesis of allergic and inflammatory diseases, such as atopic dermatitis and asthma. CCL17/TARC binds to its receptor CCR4 and mediates chemotaxis of CCR4-expressing cells, contributing to the orchestration of immune responses.

制备和贮存

溶解方法

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

保存方式

·12 months from date of receipt, -20 to -70 °C as supplied.
·1 month, 2 to 8 °C under sterile conditions after reconstitution.
·Please avoid repeated freeze-thaw cycles.

文献

Int Immunol. 1999 Jan;11(1):81-8.

数据库链接

Accession

Q92583

参考图片

2μg (R: reducing condition, N: non-reducing condition).

>95% as determined by RP-HPLC.

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货号：

UA040321-1mg

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