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品牌: Usbiological
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Purified by Protein G affinity chromatography.
反应种属:
Rabbit
产品介绍
产品介绍
产品信息
荧光素标记
HRP

抗原来源
Human

宿主
Rabbit

免疫原
Recombinant protein corresponding to aa2-170 from human cyclin-Y.

产品用途
Suitable for use in ELISA. Other applications not tested.

简单描述
Positive regulatory subunit of the cyclin-dependent kinases CDK14/PFTK1 and CDK16. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Recruits CDK16 to the plasma membrane. Isoform 3 might play a role in the activation of MYC-mediated transcription.

同种型
IgG

克隆类别
Polyclonal

纯度
Purified by Protein G affinity chromatography.

形式
Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol. Labeled with horseradish peroxidase (HRP).

应用
实验应用
E

推荐用量
Optimal dilutions to be determined by the researcher.

反应种属
Rabbit

交叉反应性
Hu

目标/特异性
Recognizes human CCNY.

稀释度
Optimal dilutions to be determined by the researcher.
背景
别名
Cyclin-Y (Cyc-Y) (Cyclin box protein 1) (Cyclin fold protein 1) (cyclin-X), CCNY, C10orf9 CBCP1 CFP1

制备和贮存
保存方式
Storage_Temp:-20°C
Storage_and_Stability:Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
数据库链接
UniProt ID
Q8ND76

SwissProt
Q8ND76

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