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CD1E
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产品介绍
产品介绍
产品信息
抗原来源
Human
宿主
Rabbit
免疫原
Synthetic peptide corresponding to the middle region of Human CD1E
产品用途
Suitable for use in Western Blot. Other applications not tested.
简单描述
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes within Golgi compartments, endosomes, and lysosomes, and is cleaved into a stable soluble form. The soluble form is required for the intracellular processing of some glycolipids into a form that can be presented by other CD1 family members. Many alternatively spliced transcript variants encoding different isoforms have been described. Additional transcript variants have been found; however, their biological validity has not been determined.
同种型
IgG
克隆类别
Polyclonal
纯度
Purified by affinity chromatography.
形式
Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.
基因
CD1E
应用
实验应用
WB
推荐用量
Optimal dilutions to be determined by the researcher.
反应种属
Rabbit
交叉反应性
Hu
目标/特异性
Recognizes human CD1E.
稀释度
Optimal dilutions to be determined by the researcher.
背景
别名
CD1E,
制备和贮存
保存方式
Storage_Temp:-20°C
Storage_and_Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
数据库链接
Entrez-Gene ID
913
UniProt ID
P15812-4
SwissProt
P15812-4
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