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产品介绍
产品介绍
产品信息
克隆号
22D1
克隆类别
单抗
Product Details
The 22D1 monoclonal antibody reacts with mouse CD209b also known as SIGN-R1. CD209b is a 37 kDa type II transmembrane C-type lectin receptor. CD209b is expressed on the surface of splenic marginal zone and lymph node medullary macrophages and is commonly used as a marker for these cells. The CD209b protein is involved in the innate immune response, it binds to and initiates uptake of various microorganisms by recognizing high-mannose-containing glycoproteins on their envelopes. The 22D1 antibody has been reported to block CD209b in vivo.Specifications
| Isotype | Armenian Hamster IgG, κ |
|---|---|
| Recommended Isotype Control(s) | InVivoMAb polyclonal Armenian hamster IgG |
| Recommended Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer |
| Conjugation | This product is unconjugated. Conjugation is available via our Antibody Conjugation Services. |
| Immunogen | C-terminal peptide of mouse SIGN-R1 |
| Reported Applications | in vivo SIGN-R1 blockade Immunohistochemistry (frozen) Western blot Flow cytometry |
| Formulation | PBS, pH 7.0 Contains no stabilizers or preservatives |
| Endotoxin | <2EU/mg (<0.002EU/μg) Determined by LAL gel clotting assay |
| Purity | >95% Determined by SDS-PAGE |
| Sterility | 0.2 µm filtration |
| Production | Purified from cell culture supernatant in an animal-free facility |
| Purification | Protein G |
| RRID | AB_2687704 |
| Molecular Weight | 150 kDa |
| Storage | The antibody solution should be stored at the stock concentration at 4°C. Do not freeze. |
组成成分
IGG-免疫球蛋白G型抗体
应用
反应种属
mouse
背景
研究领域
Cancer Biology, Cell Migration & Adhesion, Immunology, Innate Immunity
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