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产品介绍
产品介绍
产品信息
宿主
鼠
克隆号
M1/69
Product Details
The M1/69 monoclonal antibody reacts with mouse CD24 also known as heat stable antigen (HSA), a 35-50 kDa glycosylated membrane protein. CD24 is expressed by erythrocytes, granulocytes, monocytes, lymphocytes, and dendritic cells. Immature B cells in bone marrow and spleen of adult mice express high levels of CD24, while mature peripheral B cells express intermediate levels of CD24. The expression of CD24 has been used to resolve stages of B cell lymphopoiesis in mouse bone marrow. It has been reported that P-selectin (CD62P) binds to CD24. CD24 is often overexpressed in human tumors. In cancer, CD24 is a regulator of cell migration, invasion, and proliferation.Specifications
| Isotype | Rat IgG2b, κ |
|---|---|
| Recommended Isotype Control(s) | InVivoMAb rat IgG2b isotype control, anti-keyhole limpet hemocyanin |
| Recommended Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer |
| Conjugation | This product is unconjugated. Conjugation is available via our Antibody Conjugation Services. |
| Immunogen | C57BL/10 mouse splenic T cells |
| Reported Applications | in vivo administration Immunohistochemistry (frozen) Immunohistochemistry (paraffin) Immunofluorescence Flow cytometry |
| Formulation | PBS, pH 7.0 Contains no stabilizers or preservatives |
| Endotoxin | <2EU/mg (<0.002EU/μg) Determined by LAL gel clotting assay |
| Purity | >95% Determined by SDS-PAGE |
| Sterility | 0.2 µm filtration |
| Production | Purified from cell culture supernatant in an animal-free facility |
| Purification | Protein G |
| RRID | AB_2894779 |
| Molecular Weight | 150 kDa |
| Storage | The antibody solution should be stored at the stock concentration at 4°C. Do not freeze. |
组成成分
膜蛋白24抗体，磷酸盐缓冲液
应用
反应种属
Mouse
背景
研究领域
Cancer Biology, Cell Migration & Adhesion, Immunology
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