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产品介绍
产品信息
荧光素标记
纯化方式
Protein G
抗原名称
CD28
宿主
Syrian Hamster
免疫原
C57BL/6 mouse T cell lymphoma EL-4 cells
同种型
Syrian Hamster IgG2
分子量
150 kDa
克隆号
37.51
纯度
>95%(Determined by SDS-PAGE)
内毒素水平
<2EU/mg (<0.002EU/μg), 0.2 μM filtered Determined by LAL gel clotting assay
浓度
Lot specific* (generally 4 to 11 mg/ml)*
性状
Liquid
缓冲体系
PBS pH6.0 containing no preservative
产品类型
Syrian hamster mAb
应用
实验应用
in vitro T cell stimulation/activation, in vivo CD28 blockade
反应种属
Ms
背景
背景
This antibody recognizes the same epitope as clone 37.51.
This monoclonal antibody reacts with mouse CD28, a 45 kDa costimulatory receptor and a member of the lg superfamily, CD28 is expressed by thymocytes, most peripheral T cells, and NK cells. CD28 is a receptor for CD80 (B7-1) and CD86 (B7-2). Signaling through CD28 augments lL-2 and IL-2 receptor expression as well as cytotoxicity of CD3-activated T cells. This antibody has been shown to stimulate the proliferation and cytokine production by activated T and NK cells and provide a costimulatory signal for CTL induction.
制备和贮存
保存方式
The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
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