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CD320, CT (CD320, 8D6A, CD320 antigen, 8D6 antigen, FDC-signaling molecule 8D6, Transcobalamin receptor, CD320)
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产品介绍
产品介绍
产品信息
纯化方式
Affinity Purified
Purified by Protein A affinity chromatography.
抗原名称
CD320 antigen isoform 2
免疫原
CD320 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152-182 amino acids from the C-terminal region of human CD320.
商品描述
The CD320 antigen gene encodes the transcobalamin receptor (TCBLR). Cellular uptake of cobalamin (vitamin B12) is mediated by receptors expressed on the cell surface. Transcobalamin II (TCN2; MIM 613441), a plasma protein secreted by endothelial cells, binds the cobalamin absorbed in the distal ileum and carries 10 to 30% of total circulating cobalamin. CD320 encodes a transcobalamin receptor that binds TCN2-cobalamin at the plasma membrane and internalizes the complex by endocytosis (Quadros et al., 2009 [PubMed 18779389]).
形式
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
产品类型
Polyclonal
应用
实验应用
ELISA (EL/EIA), Western Blot (WB)
反应种属
Human
背景
别名
Anti -CD320, CT (CD320, 8D6A, CD320 antigen, 8D6 antigen, FDC-signaling molecule 8D6, Transcobalamin receptor, CD320)
制备和贮存
保存方式
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
数据库链接
NCBI
51293
UniProt ID
Q9NPF0
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