CD79a (C-Term) Rabbit Monoclonal Antibody (Clone RM297)

Rabbit

Peptide from the C-terminal region of human CD79a

CD79a is a member of the heterodimeric signal transduction component of the B cell receptor (BCR) complex that is encoded by CD79A/MB-1 in humans.1 It is composed of a disulfide-linked extracellular domain, a transmembrane region, and a cytoplasmic tail containing an immunoreceptor tyrosine-based activation motif that facilitates intracellular signaling.1,2 CD79a is expressed exclusively in B cells and B cell progenitors, and is commonly used as a B cell marker. It is co-expressed at the cell surface with CD79b and immunoglobulins of all isotypes as the mature BCR complex.1 Mutations in CD79A/MB-1 have been found in patients with autosomal recessive agammaglobulinemia.3 Cayman's CD79a (C-Term) Rabbit Monoclonal Antibody (Clone RM297) can be used for immunohistochemistry (IHC) and Western blot (WB) applications.WARNING This product is not for human or veterinary use.

For immunochemical detection of CD79a

IgG

RM297

Antibodies/Primary Antibodies/Monoclonal Antibodies

Immunohistochemistry,Western Blot

(+) Human

(+) CD79a

Synonyms:B Cell Antigen Receptor Complex-associated Protein α Chain Igα MB-1 Membrane Glycoprotein

≥ 1 year