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InVivoMAb anti-mouse CD80 (B7-1)
品牌： BioXcell
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对比
咨询反应种属：
mouse
来源宿主：
亚美尼亚仓鼠
产品介绍
产品介绍
产品信息
宿主
亚美尼亚仓鼠
克隆号
1G10
克隆类别
单抗
Product Details
The 1G10 monoclonal antibody reacts with mouse CD80 also known as B7-1. CD80 is a 60 kDa Ig superfamily member and is expressed by activated B cells and constitutively by monocytes and dendritic cells. This ligand binds to CD28 to provide a costimulatory signal necessary for T cell activation and survival, and cytokine production. Additionally, CD80 binds to CTLA-4 which inhibits T cells. This antibody has been shown to block CD80 in vivo.Specifications
| Isotype | Rat IgG2a, κ |
|---|---|
| Recommended Isotype Control(s) | InVivoMAb rat IgG2a isotype control, anti-trinitrophenol |
| Recommended Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer |
| Conjugation | This product is unconjugated. Conjugation is available via our Antibody Conjugation Services. |
| Immunogen | Dibutyryl cAMP-Activated 5C2 cells |
| Reported Applications | in vivo CD80 blockade Affinity chromatography |
| Formulation | PBS, pH 7.0 Contains no stabilizers or preservatives |
| Endotoxin | <2EU/mg (<0.002EU/μg) Determined by LAL gel clotting assay |
| Purity | >95% Determined by SDS-PAGE |
| Sterility | 0.2 µm filtration |
| Production | Purified from cell culture supernatant in an animal-free facility |
| Purification | Protein G |
| RRID | AB_10950113 |
| Molecular Weight | 150 kDa |
| Storage | The antibody solution should be stored at the stock concentration at 4°C. Do not freeze. |
组成成分
共刺激分子蛋白80抗体，磷酸盐缓冲液
应用
反应种属
mouse
背景
研究领域
Cancer Biology, Immune Checkpoint Protein, Immunology, Innate Immunity
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