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CD8α Recombinant Mouse mAb (SDT-126-8)
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CD8α Recombinant Mouse mAb (SDT-126-8)

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品牌: STARTER
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反应种属:
Hu
来源宿主:
Mouse
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产品介绍
产品介绍
产品信息
纯化方式
Protein G
抗原名称
CD8α
宿主
Mouse
免疫原
Synthetic Peptide
同种型
IgG1,k
克隆号
SDT-126-8
浓度
2 mg/ml
性状
Liquid
缓冲体系
PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
产品类型
Mouse mAb
应用
实验应用
IHC-P
反应种属
Hu
稀释度
  • IHC-P

    1:2000
背景
别名
T-lymphocyte differentiation antigen T8/Leu-2, T-cell surface glycoprotein CD8 alpha chain, MAL, CD8a
背景

CD8A encodes the CD8 alpha chain of the αβT cells, proposed as a quantifiable indicator for CD8+ CTL recruitment or activity assessments and a robust biomarker for responses to anti-PD-1/PD-L1 therapy.In NK-cells, the presence of CD8A homodimers at the cell surface provides a survival mechanism allowing conjugation and lysis of multiple target cells. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells.

细胞定位
Cell membrane
制备和贮存
保存方式

12 months from date of receipt / reconstitution, -20 °C as supplied

数据库链接
Accession

参考图片

IHC shows positive staining in paraffin-embedded human stomach. Anti-CD8α antibody was used at 1/1000 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

IHC shows positive staining in paraffin-embedded human tonsil. Anti-CD8α antibody was used at 1/1000 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

IHC shows positive staining in paraffin-embedded human tonsil. Anti-CD8α antibody was used at 1/1000 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

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货号:
S0B2148-500ul
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