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Cdc20 Ab (CDC20/7026R)
品牌： Novus
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对比
咨询分子量：
55 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
纯度：
Protein A or G purified
产品介绍
产品介绍
产品信息
荧光素标记
Unconjugated
宿主
Rabbit
免疫原
Recombinant human Cdc20 protein (Uniprot: Q12834 )
简单描述
200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP3-14078)
Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80 C.
商品描述
200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP3-14078)
Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80 C.
同种型
IgG Kappa
分子量
55 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
克隆号
CDC20/7026R
克隆类别
Monoclonal
纯度
Protein A or G purified
浓度
0.2 mg/ml
防腐剂
0.05% Sodium Azide
基因
CDC20
应用
实验应用
IHC
反应种属
Hu
稀释度
Immunohistochemistry-Paraffin 1-2 ug/ml
背景
别名
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
背景
CDC20 is a WD repeat containing cell cycle-regulator that binds to and activates the ubiquitin-ligase activity of the APC/c (anaphase-promoting complex/cyclosome). APC/c ubiquitinating activity is responsible for the degradation of securin and cyclin B that prompts the onset of anaphase and exit from mitosis. CDC20 has also been reported to form a complex with histone deacetylases and can function as a transcriptional repressor involved in cell cycle arrest. As a regulator of APC/c activity, CDC20 plays a key role in the spindle-assembly checkpoint.
细胞定位
Cytoplasm
制备和贮存
保存方式
Store at 4C.
数据库链接
UniProt ID
Q12834(Human)
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