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Cellular Apoptosis Susceptibility, NT (Exportin-2, Exp2, Importin-alpha Re-exporter, Chromosome Segregation 1-like Protein, Cellular Apoptosis Suscept


品牌: MyBioSource








反应种属:
Human
实验应用:
Western Blot (WB), Immunohistochemistry (IHC)
产品介绍
产品介绍
产品信息
纯化方式
Affinity Purified
Purified by immunoaffinity chromatography.

抗原名称
cellular apoptosis susceptibility protein

免疫原
Synthetic peptide corresponding to human CSE1L at N-terminal.

商品描述
Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation.

形式
Supplied as a liquid in 10mM PBS, pH 7.4, BSA, sodium azide.

产品类型
Polyclonal

应用
实验应用
Western Blot (WB), Immunohistochemistry (IHC)

反应种属
Human

背景
别名
Anti -Cellular Apoptosis Susceptibility, NT (Exportin-2, Exp2, Importin-alpha Re-exporter, Chromosome Segregation 1-like Protein, Cellular Apoptosis Susceptibility Protein, CSE1L, CAS, XPO2)

制备和贮存
保存方式
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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