Clathrin LC (3F133)

mouse

Clathrin Light Chain抗体(3F133)是小鼠单克隆IgG2b κ, 在2篇文献中引用，规格为200 µg/mlraised against amino acids 23-44 of Clathrin LC of Clathrin light chain of bovine origin推荐用于 mouse, rat, human, bovine, Xenopus 和 zebrafish 来源的Clathrin LCA and LCB WB, IP, IF 和 IHC(P)检测m-IgG2b BP-HRP 和 m-IgGκ BP-HRP 是 Clathrin Light Chain Antibody (3F133) for WB and IHC(P) 首选应用二抗. 这些试剂现在以套形式提供 Clathrin Light Chain Antibody (3F133) (见下方订购信息). 查看产品引用文献(2) Clathrin is a major cytosolic coat protein in pits and vesicles originating from the plasma membrane and the trans-Golgi network. In receptor-mediated endocytosis, receptor proteins are engulfed by clathrin-coated vesicles. Clathrin is composed of three heavy chains and three light chains which associate non-covalently to form a triskelion structure. Clathrin light chain regulates the self-assembly of triskelions onto intracellular membranes. Clathrin light chain subunits (LCA and LCB) contribute to regulation of coated vesicle formation to sort proteins during receptor-mediated endocytosis and organelle biogenesis. Although LCA and LCB are encoded by two discrete genes sharing only 60% homology, they have certain features in common. Both LCA and LCB undergo alternative mRNA splicing, which results in the generation of tissue-specific isoforms. Additionally, in the brain, LCA and LCB contain inserted sequences that form higher molecular weight isoforms. These sequences insert at similar cytoplasmic domain encoding regions for both LCA and LCB.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Replacement monoclonal antibody for: sc-28276, sc-323740.

IGG-免疫球蛋白G型抗体

HumanCLTA

WB, IP, IF, IHC(P)

1211, 1212;12757, 74325,