SH-PTP1 (PTY6)

mouse

SH-PTP1抗体(PTY6)是小鼠单克隆IgG1 κ, 在1篇文献中引用，规格为100 µg/mlraised against recombinant full length SH-PTP1 of human origin推荐用于 human 来源的SH-PTP1 WB, IP, IF 和 ELISA检测看 SH-PTP1 (D-11): sc-7289，可查看有标记的 SH-PTP1 抗体，包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790目前，我们还没有完成SH-PTP1 抗体 (PTY6)的首选二抗检测试剂的鉴定。这项工作正在进行中。 查看产品引用文献(1) The steady state of protein tyrosyl phosphorylation in cells is regulated by the opposing action of tyrosine kinases and protein tyrosine phosphatases (PTPs). Several groups have independently identified a non-transmembrane PTP, designated SH-PTP1 (also known as PTP1C, HCP and SHP), which is primarily expressed in hematopoietic cells and characterized by the presence of two SH2 domains N-terminal to the PTP domain. SH2 domains generally mediate the association of regulatory molecules with specific phosphotyrosine-containing sites on autophosphorylated receptors, thereby controlling the initial interaction of receptors with these substrates. A second and much more widely expressed PTP with SH2 domains, SH-PTP2 (also designated PTP1D and Syp), has been identified. Strong sequence similarity between SH-PTP2 and the Drosophila gene corkscrew (CSW) and their similar patterns of expression suggest that SH-PTP2 is the human corkscrew homolog.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

IGG-免疫球蛋白G型抗体

HumanPTPN6

WB, IP, IF, ELISA

5777