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COL23A1 (Collagen alpha-1(XXIII) Chain, DKFZp434K0621)
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产品介绍
产品信息
纯化方式
Affinity Purified
Purified by Protein A affinity chromatography.
抗原名称
collagen alpha-1(XXIII) chain
免疫原
Full length human COL23A1, aa1-309 (AAH42428.1).
商品描述
Collagen XXIII a1 (COL23A1) is an epithelial cell type 2 transmembrane glycoprotein with multiple collagen-like domains in its extracellular region. Intracellular furin-mediated cleavage of the molecule generates a 58kD shed fragment that forms disulfide-linked trimers. An alternately spliced isoform consists of nearly 300aa of the membrane proximal extracellular domain (ECD), flanked by substituted sequences. COL23A1 is upregulated in many transformed cell lines and serves as an indicator for tumor aggressiveness in prostate cancer. Within the ECD, human COL23A1 shares 89% aa sequence identity with mouse and rat COL23A1.
形式
Supplied as a liquid in PBS, pH 7.2.
产品类型
Polyclonal
应用
实验应用
Western Blot (WB)
反应种属
Human
背景
别名
Anti -COL23A1 (Collagen alpha-1(XXIII) Chain, DKFZp434K0621)
制备和贮存
保存方式
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
数据库链接
NCBI
91522
UniProt ID
Q86Y22
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