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产品介绍
产品介绍
产品信息
抗原名称
β-amyloid
商品描述
Compound E is a γ-secretase inhibitor. Compound E bloks β-amyloid(40), β-amyloid(42), and Notch γ-secretase cleavage with IC50s of 0.24, 0.37, 0.32 nM, respectively.
分子量
490.50
纯度
≥98%
可溶性
DMSO : 80 mg/mL (163.10 mM)
外观
White to off-white powder
In vitro(体外研究)
Compound E reduces the proliferation of T47D, and MCF-7 cell lines by less than 50% at a concentration of 50 μM.
背景
分子式
C27H24F2N4O3
CAS号
209986-17-4
PK值
pKa: 12.54 (Predicted), pKb: 3.05 (Predicted)
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
参考图片
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