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产品介绍
产品介绍
产品信息
抗原名称
GSK-3
商品描述
CP21R7是强的和选择性的GSK-3β抑制剂。
分子量
317.34
纯度
98%
可溶性
Ethanol :1 mg/mL (3.15 mM)
DMSO :59 mg/mL (185.9 mM)
DMSO :59 mg/mL (185.9 mM)
In vitro(体外研究)
CP21R7 (Compound 9) is a selective inhibitor of GSK-3β, with an IC50 of 1.8 nM; the IC50 of CP21R7 against PKCα is 1900 nM. CP21R7 (CP21, 3 μM) potently activates canonical Wnt signaling with highest activity. CP21 significantly increases total levels of intracellular β-catenin. CP21 combined with BMP4 induces commitment of hPSCs towards mesoderm.
背景
别名
CP21
分子式
C19H15N3O2
CAS号
125314-13-8
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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