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产品介绍
产品介绍
产品信息
宿主
鼠
克隆号
5A1
克隆类别
单抗
Product Details
The 5A1 monoclonal antibody reacts with mouse colony stimulating factor 1 (CSF1) also known as macrophage colony-stimulating factor (M-CSF). CSF1 is a hematopoietic growth factor that is expressed by many different cell types including fibroblasts, stromal cells, osteoblasts, activated T cells, macrophages, and B cells. CSF1 plays a role in regulating the proliferation, differentiation and survival of monocytes, macrophages, and bone marrow progenitor cells. CSF1 produced in vessel walls is thought to contribute to the development and progression of atherosclerosis. The 5A1 antibody has been shown to neutralize CSF1 in vivo.Specifications
| Isotype | Rat IgG1, κ |
|---|---|
| Recommended Isotype Control(s) | InVivoMAb rat IgG1 isotype control, anti-horseradish peroxidase |
| Recommended Dilution Buffer | InVivoPure pH 8.0 Dilution Buffer |
| Conjugation | This product is unconjugated. Conjugation is available via our Antibody Conjugation Services. |
| Immunogen | Purified mouse CSF-1 |
| Reported Applications | in vivo CSF1 neutralization |
| Formulation | PBS, pH 8.0 Contains no stabilizers or preservatives |
| Endotoxin | <2EU/mg (<0.002EU/μg) Determined by LAL gel clotting assay |
| Purity | >95% Determined by SDS-PAGE |
| Sterility | 0.2 µm filtration |
| Production | Purified from cell culture supernatant in an animal-free facility |
| Purification | Protein G |
| RRID | AB_10950309 |
| Molecular Weight | 150 kDa |
| Storage | The antibody solution should be stored at the stock concentration at 4°C. Do not freeze. |
组成成分
集落刺激因子蛋白抗体，磷酸盐缓冲液
应用
反应种属
mouse
背景
研究领域
Cytokine and Chemokine
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