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产品介绍
产品介绍
产品信息
克隆号
2-4A5-4
Product Details
The 2-4A5-4 monoclonal antibody reacts with human colony stimulating factor 1 receptor (CSF1R), also known as macrophage colony-stimulating factor receptor (M-CSFR), CD115, and c-fms. CSF1R is a single-pass type I membrane protein and member of the platelet-derived growth factor receptor family. CSF1R is expressed by monocytes/macrophages, peritoneal exudate cells, plasmacytoid and conventional dendritic cells, and osteoclasts. CSF1R is a receptor for CSF1 and CSF1. Signaling through CSF1R regulates the proliferation and differentiation of cells in the monocytic lineage.Specifications
| Isotype | Rat IgG1, κ |
|---|---|
| Recommended Isotype Control(s) | InVivoMAb rat IgG1 isotype control, anti-horseradish peroxidase |
| Recommended Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer |
| Conjugation | This product is unconjugated. Conjugation is available via our Antibody Conjugation Services. |
| Immunogen | Rat NRK cells expressing transduced human CSF1R |
| Reported Applications | in vitro CSF1R neutralization Immunohistochemistry (paraffin) Functional assays Flow cytometry |
| Formulation | PBS, pH 7.0 Contains no stabilizers or preservatives |
| Endotoxin | <2EU/mg (<0.002EU/μg) Determined by LAL gel clotting assay |
| Purity | >95% Determined by SDS-PAGE |
| Sterility | 0.2 µm filtration |
| Production | Purified from cell culture supernatant in an animal-free facility |
| Purification | Protein G |
| RRID | AB_2894766 |
| Molecular Weight | 150 kDa |
| Storage | The antibody solution should be stored at the stock concentration at 4°C. Do not freeze. |
组成成分
巨噬细胞集落刺激因子受体抗体，磷酸盐缓冲液
应用
反应种属
Human
背景
研究领域
Cancer Biology, Cytokine Receptor, Immunology, Innate Immunity
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