CXCR3

Synthetic peptide corresponding to human CXCR3.

Suitable for use in ELISA, Immunohistochemistry. Other applications not tested.

This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10kD protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4.

IgG

Polyclonal

Purified by immunoaffinity chromatography.

Suitable for use in ELISA, Immunohistochemistry. Other applications not tested.

Immunohistochemistry: 1:25-1:100 Optimal dilutions to be determined by the researcher.

Rabbit

Hu Mo Rt

Recognizes human CXCR3. Species Crossreactivity: mouse and rat

GPR9, MigR, CD182, CD183, Mig-R, CKR-L2, CMKAR3, IP10-R

P49682