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Cytochrome c (136F3) Rabbit mAb
品牌： CST
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对比
咨询分子量：
14
反应种属：
Human,Mouse,Rat,Hamster,Monkey,
产品介绍
产品介绍
产品信息
荧光素标记
Unconjugated
抗原名称
Cytochrome c
来源纯化
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro72 of human cytochrome c protein.
宿主
Rabbit
商品描述
Product Usage Information
| Application | Dilution |
|---|---|
| Western Blotting | 1:1000 |
| Immunohistochemistry (Paraffin) | 1:50 - 1:200 |
同种型
Rabbit IgG
分子量
14
研究领域
癌症,细胞生物学,纤维化,神经科学,
应用
反应种属
Human,Mouse,Rat,Hamster,Monkey,
目标/特异性
Specificity/Sensitivity
Cytochrome c (136F3) Rabbit mAb detects endogenous levels of total cytochrome c protein.
Species Reactivity:
Human, Mouse, Rat, Hamster, Monkey
敏感性
Endogenous
背景
背景
Cytochrome c is a well conserved electron-transport protein and is part of the respiratory chain localized to mitochondrial intermembrane space (1). Upon apoptotic stimulation, cytochrome c released from mitochondria associates with procaspase-9 (47 kDa)/Apaf 1. This complex processes caspase-9 from inactive proenzyme to its active form (2). This event further triggers caspase-3 activation and eventually leads to apoptosis (3).
1.Schagger H.H. et al. (2002) Biochem. Biophys. Acta. 1555, 154-159.
2.Li, P. et al. (1997) Cell 91, 479-489.
3.Liu, X. et al. (1996) Cell 86, 147-157.
研究领域
癌症,细胞生物学,纤维化,神经科学,
翻译后修饰
unmodified
制备和贮存
保存方式
Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
数据库链接
Entrez-Gene ID
54205
UniProt ID
P99999
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