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Cynomolgus Interferon alpha-B / IFNA8 Protein (His Tag)
品牌： Sino Biological
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对比
咨询分子量：
The recombinant cynomolgus IFNA8 comprises 177 amino acids and has a calculated molecular mass of 21 KDa. The apparent molecular mass of it is approximately 33 KDa respectively in SDS-PAGE.
纯度：
> 95 % as determined by SDS-PAGE
产品介绍
产品介绍
产品信息
抗原名称
interferon, alpha 8
N端序列分析
Leu 33
分子量
The recombinant cynomolgus IFNA8 comprises 177 amino acids and has a calculated molecular mass of 21 KDa. The apparent molecular mass of it is approximately 33 KDa respectively in SDS-PAGE.
生物活性
Measured in antiviral assays using WISH cells infected with vesicular stomatitis virus.
The ED50 for this effect is typically 1-5 pg/mL.
纯度
> 95 % as determined by SDS-PAGE
内毒素水平
< 1.0 EU per μg of the protein as determined by the LAL method
形式
Lyophilized from sterile PBS, PH 7.4.
Please contact us for any concerns or special requirements.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
表达系统
HEK293
应用
反应种属
Cynomolgus
背景
背景
Interferon alpha-B, also known as IFNA8, belongs to the alpha/beta interferon family. Interferons are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites, or tumor cells. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They also allow for communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. Interferons also activate immune cells, such as natural killer cells and macrophages. They increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymphocytes. They also increase the ability of uninfected host cells to resist new infections by virus. Certain symptoms, such as aching muscles and fever, are related to the production of IFNs during infection. Produced by macrophages, IFN-alpha has antiviral activities.
Full Name
interferon, alpha 8
References
Henco K. et al., 1985, J Mol Biol. 185 (2): 227-60. Goeddel DV. et al., 1981, Nature. 290 (5801): 20-6. Yelverton E. et al., 1981, Nucleic Acids Res. 9 (3): 731-41. Kempaiah P. et al., 2012, Hum Genet. 131 (8): 1375-91.
制备和贮存
保存方式
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
数据库链接
Accession
G7PS89
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