DCLRE1C (DNA Cross-Link Repair 1C, Protein Artemis)

Synthetic peptide corresponding to the C-terminal region of human DCLRE1C

Suitable for use in Western Blot. Other applications not tested.

DCLRE1C is a nuclear protein that is involved in V(D)J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide. Mutations in this gene cause Athabascan-type severe combined immunodeficiency (SCIDA). This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide. Mutations in this gene cause Athabascan-type severe combined immunodeficiency (SCIDA).

IgG

Polyclonal

Purified by affinity chromatography.

DCLRE1C

Suitable for use in Western Blot. Other applications not tested.

Optimal dilutions to be determined by the researcher.

Rabbit

Hu

Recognizes human DCLRE1C.

A-SCID, DCLREC1C, FLJ11360, FLJ36438, RS-SCID, SCIDA, SNM1C, hSNM1C

64421

Q96SD1