D-DELTA-(P)生育三烯酚

δ-Tocotrienol is one of the forms of vitamin E (four tocopherols (α, β, δ, and γ) and four tocotrienols (α, β, δ, and γ)), which is known for its antioxidant activity. At 0.1-10 µM, δ-tocotrienol significantly suppresses H2O2-induced cell death of rat striatal neurons and provides protection against S-nitrocysteine-induced cell death and SIN-1 cytotoxicity in a concentration dependent manner. At concentrations of 10 µM, δ-tocotrienol displays more inhibitory action on adhesiveness of HAECs to U937 monocytic cells, via inhibition of VCAM-1 expression, than α-tocopherol and other tocotrienols at the same concentration.

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