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产品介绍
产品介绍
产品信息
商品描述
3,4-Dihydroxyphenylethanol is an active ingredient that extracted from olive. It is one of the most efficient and secure antioxidant and can be used in the cardiovascular drugs。
分子量
154.16
纯度
＞98%
可溶性
Soluble in water (50mg/ml)
外观
油状液体
In vitro(体外研究)
Hydroxytyrosol decreases the intracellular reactive oxygen species (ROS) level in MCF10A cells but not in MCF7 or MDA-MB-231 cells. Hydroxytyrosol prevents oxidative DNA damage in the three breast cell lines: MCF10A, MDA-MB-231 and MCF7 cells. It is a potent antioxidant because of its marked antioxidant activity, its ability to scavenge oxygen and nitrogen free radicals, to inhibit Low Density Lipoprotein (LDL) oxidation, platelet aggregation and endothelial cell activation and its protection against DNA damage. Hydroxytyrosol is able to reduce the synthesis of prostaglandin E2 blocking the transcription of COX-2 and 5-lipooxygenase, thereby reducing the chronic influence associated with diseases such as cancer.
In vivo(体内研究)
HT administration protects against hepatic I/R injury, as indicated by the decreased levels of serum aminotransferase and less parenchymal necrosis and apoptosis. Serum levels of tumor necrosis factor-α, interleukin-6, macrophage inflammatory protein 2, as well as reactive oxygen species (ROS) content in liver tissues, are all decreased by HT.
背景
别名
2-(3,4-Dihydroxyphenyl)ethyl alcohol；3-Hydroxytyrosol
分子式
C8H10O3
CAS号
10597-60-1
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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