DLG4 (FITC)

Recombinant protein corresponding to aa551-724 from human disks large homolog 4 protein.

Suitable for use in FLISA. Other applications not tested.

Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B (By similarity).

IgG

Polyclonal

Purified by immunoaffinity chromatography.

Suitable for use in FLISA. Other applications not tested.

Optimal dilutions to be determined by the researcher.

Rabbit

Hu

Recognizes human DLG4.

Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90), DLG4, PSD95

P78352