DLX5 (FITC)

Recombinant protein corresponding to aa1-249 from human homeobox protein DLX-5.

Suitable for use in FLISA. Other applications not tested.

Transcriptional factor involved in bone development. Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation. Stimulates ALPL promoter activity in a RUNX2-independent manner during osteoblast differentiation. Stimulates SP7 promoter activity during osteoblast differentiation. Promotes cell proliferation by up-regulating MYC promoter activity. Involved as a positive regulator of both chondrogenesis and chondrocyte hypertrophy in the endochondral skeleton. Binds to the homeodomain-response element of the ALPL and SP7 promoter. Binds to the MYC promoter. Requires the 5'-TAATTA-3' consensus sequence for DNA-binding.

IgG

Polyclonal

Purified by Protein G affinity chromatography.

Suitable for use in FLISA. Other applications not tested.

Optimal dilutions to be determined by the researcher.

Rabbit

Hu

Recognizes human DLX5.

Homeobox protein DLX-5, DLX5

P56178