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DNAI1 (Dynein Intermediate Chain 1, Axonemal, Axonemal Dynein Intermediate Chain 1)
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产品介绍
产品介绍
产品信息
纯化方式
Affinity Purified
Purified by Protein A affinity chromatography.
抗原名称
dynein intermediate chain 1, axonemal isoform 2
免疫原
Full length recombinant corresponding to aa1-700 from human DNAI1 (AAH30583) with GST tag. MW of the GST tag alone is 26kD.
商品描述
The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. This gene encodes an intermediate chain dynein, belonging to the large family of motor proteins. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia (PCD) and Kartagener syndrome.
克隆号
2D10-2A5
形式
Supplied as a liquid in PBS, pH 7.4.
产品类型
Monoclonal
应用
实验应用
ELISA (EIA), Western Blot (WB)
反应种属
Human
背景
别名
Anti -DNAI1 (Dynein Intermediate Chain 1, Axonemal, Axonemal Dynein Intermediate Chain 1)
制备和贮存
保存方式
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
数据库链接
NCBI
27019
UniProt ID
Q9UI46
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