DSPE-PEG(2000)-amine (sodium salt)

A PEGylated derivative of DSPE

DSPE-PEG(2000)-amine is a PEGylated derivative of 1,2-distearoyl-sn-glycero-3-PE (DSPE; Item No. 15095). It has been used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents.1,2,3 DSPE-PEG(2000)-amine has also been used in the synthesis of fluorescein isothiocyanate-loaded mesoporous silica nanoparticles for imaging applications.4 It can be conjugated to a variety of functional molecules for improved cellular targeting and uptake of DSPE-PEG(2000)-amine-containing nanoparticles.4,5

≥95%

1,2-distearoyl-sn-glycero-3-PE-N-[amino(polyethylene glycol)-2000]|1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-N-[amino(polyethylene glycol)-2000]|1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(polyethylene glycol)-2000]|1,2-DSPE-PEG(2000)-amine

O=[P](OCCNC(OCCOCCN)=O)(O)OCC(COC(CCCCCCCCCCCCCCCCC)=O)OC(CCCCCCCCCCCCCCCCC)=O.[Na]

(C2H4O)n C44H86N2O10P • Na

1292302-96-5

≥ 4 years

DMF: 11 mg/ml Ethanol: 20 mg/ml