全部商品分类
用小程序，查商品更便捷
Gly33-Lys417&&ILe291-Glu497
65kDa (Reducing)
1μg (R: reducing condition, N: non-reducing condition).
DT3C consists of diphtheria toxin (DT) lacking the receptor-binding domain but containing the C1, C2, and C3 domains of Streptococcus protein G (3C). When a mAb–DT3C conjugate, which functions in vitro like an ADC, reduces the viability of cancer cells, the mAb being tested must have been internalized by the target cells. DT3C can thus be a tool to identify efficiently and easily mAbs that can be internalized by cells, thereby enhancing the development of promising ADCs.
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
·12 months from date of receipt, -20 to -70 °C as supplied.
·1 month, 2 to 8 °C under sterile conditions after reconstitution.
·Please avoid repeated freeze-thaw cycles.
Biochem Biophys Res Commun. 2014 Nov 28; 454(4):600-3.Epub 2014 Nov 1.
参考图片
1μg (R: reducing condition, N: non-reducing condition).
>90% as determined by RP-HPLC.