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产品介绍
产品信息
商品描述
DuP 105 is an oral oxazolidinone, a novel synthetic antimicrobial compound effective against gram-positive bacteria.
分子量
296.34
纯度
98%
可溶性
DMSO:45 mg/mL (151.85 mM)
In vitro(体外研究)
DuP 105 MICs for 50% of the 216 gram-positive isolates tested (MIC50s) range from 4.0 to 16 μg/mL.DuP 105 shows inhibitory activities against staphylococcal isolates and B. fragilis isolates with MIC90s of 4 to 16 μg/mL and 16 μg/mL.
In vivo(体内研究)
DuP 105 administered by either the oral or the parenteral route is protective against staphylococcal and streptococcal infections in mice with the 50% effective doses of 9 to 23 mg/kg.
背景
分子式
C13H16N2O4S
CAS号
96800-41-8
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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