
首页
Edc4 (H-12)

产品介绍
产品信息
宿主
鼠

简单描述
抗-Edc4 抗体 H-12 是小鼠单克隆 IgG3 κ,Edc4抗体, 在5篇文献中引用,规格为200 µg/ml特异性抗原位于human物种的Edc4的内部区域内的氨基酸457-491之间推荐用于 mouse, rat 和 human 来源的Edc4 WB, IP, IF, IHC(P) 和 ELISA检测关于如何获取Edc4 (H-12): sc-376382的免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。m-IgG Fc BP-HRP 和 m-IgGκ BP-HRP 是 Edc4 Antibody (H-12) for WB and IHC(P) 的首选应用二抗。这些试剂现在以套装形式提供Edc4 Antibody (H-12)。 (见下方订购信息).
查看产品引用文献(5) Edc4 Antibody (H-12) is a high quality monoclonal Edc4 antibody (also designated Edc4 antibody) suitable for the detection of the Edc4 protein of mouse, rat and human origin. Edc4 Antibody (H-12) is available as the non-conjugated anti-Edc4 antibody. The major eukaryotic mRNA decay pathway occurs through deadenylation, decapping, and 5′ to 3′ degradation of the mRNA. Decapping is a critical control point in this decay pathway. Edc4 (enhancer of mRNA decapping 4), also known as human enhancer of decapping large subunit (HEDLS), RCD-8 or Ge-1, is a 1,401 amino acid protein belonging to the WD repeat EDC4 family that is involved in mRNA decapping during mRNA degradation. As part of the mRNA degradation process, Edc4 becomes part of a complex that also contains hDcp1a, hDcp2a, RCK and Edc3. Localizing to P-body and cytoplasm, Edc4 contains a nuclear localization sequence (NLS) which enables it to selectively enter the nucleus as well. Edc4 becomes phosphorylated upon DNA damage and exists as two alternatively spliced isoforms that are encoded by a gene that maps to human chromosome 16q22.1.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

克隆类别
Replacement monoclonal antibody for: sc-137444.

组成成分
信使核糖核酸脱膜蛋白4增强子抗体、磷酸缓冲盐溶液
