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产品介绍
产品介绍
产品信息
荧光素标记
Unlabeled

宿主
Mouse

商品描述
Purified Mouse Monoclonal Antibody (Mab)

同种型
IgG1,κ

分子量
Predicted molecular weight: 134 kDa

克隆号
51CT78.40.5

克隆类别
Monoclonal Antibody

应用
实验应用
WB: 1:2000, IHC-P: 1:100-500, FCM: 1:25

反应种属
Human

目标/特异性
Purified His-tagged EGFR protein(Fragment) was used to produced this monoclonal antibody.

背景
别名
EGFR抗体

研究领域
Cancer;Signal Transduction
翻译后修饰
Unmodified

细胞定位
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Nucleus membrane; Single-pass type I membrane protein Endosome Endosome membrane. Nucleus. Note=In response to EGF, translocated from the cell membrane to the nucleus via Golgi and ER (PubMed:20674546, PubMed:17909029). Endocytosed upon activation by ligand (PubMed:2790960, PubMed:17182860, PubMed:27153536, PubMed:17909029). Colocalized with GPER1 in the nucleus of estrogen agonist-induced cancer-associated fibroblasts (CAF) (PubMed:20551055)

制备和贮存
存储溶液
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

保存方式
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
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