EIF3H, NT (EIF3H, EIF3S3, Eukaryotic translation initiation factor 3 subunit H, Eukaryotic translation initiation factor 3 subunit 3, eIF-3-gamma, eIF

Affinity Purified Purified by Protein A affinity chromatography.

Eukaryotic translation initiation factor 3 subunit H

EIF3H antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-99 amino acids from the N-terminal region of human EIF3H.

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Polyclonal

ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)

Human

Anti -EIF3H, NT (EIF3H, EIF3S3, Eukaryotic translation initiation factor 3 subunit H, Eukaryotic translation initiation factor 3 subunit 3, eIF-3-gamma, eIF3 p40 subunit)

100190645

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