ERK 2 (H-9)

鼠

ERK 2抗体(H-9)是小鼠单克隆IgG2a κ, 在5篇文献中引用，规格为200 µg/mlspecific for an epitope mapping between amino acids 276-333 within subdomain XI of rat ERK 2-encoded MAP kinase p42推荐用于 mouse, rat， human 和 avian 来源的ERK 2 p42 WB, IP, IF, IHC(P) 和 ELISA检测; 也和以下物种反应，包括： 和 canine, bovine, porcine and avian看 ERK 2 (D-2): sc-1647，可查看有标记的 ERK 2 抗体，包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790m-IgG Fc BP-HRP and m-IgG2a BP-HRP 是 ERK 2 Antibody (H-9) for WB and IHC(P)首选应用二抗。这些试剂现在以套装形式提供ERK 2 Antibody (H-9) (见下方订购信息). 查看产品引用文献(5) Mitogen-activated protein kinase (MAPK) signaling pathways involve two closely related MAP kinases, known as extracellular-signal-related kinase 1 (ERK 1, p44) and 2 (ERK 2, p42). Growth factors, steroid hormones, G protein-coupled receptor ligands, and neurotransmitters can initiate MAPK signaling pathways. Activation of ERK1 and ERK2 requires phosphorylation by upstream kinases such as MAP kinase kinase (MEK), MEK kinase and Raf-1. ERK1 and ERK2 phosphorylation can occur at specific tyrosine and threonine sites mapping within consensus motifs that include the Threonine-Glutamate-Tyrosine motif. ERK activation leads to dimerization with other ERKs and subsequent localization to the nucleus. Active ERK dimers phosphorylate serine and threonine residues on nuclear proteins and influence a host of responses that include proliferation, differentiation, transcription regulation and development. The human ERK2 gene maps to chromosome 22q11.21 and encodes a 360-amino acid protein.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

丝裂原活化蛋白激酶抗体，磷酸盐缓冲液

HumanMAPK1

m, r, h

5594;26413