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产品介绍
产品信息
商品描述
Erlontinib-d6 hydrochloride potently inhibits EGFR autophosphorylation in cultured human head and neck tumor cells, a cell line which exhibits high levels of EGFR. Erlotinib-d6 HCl also inhibits the proliferation of PC-9 cell lines, which contain a deletion mutation on exon 19 of the EGFR gene. A combination of Erlotinib-d6 HCl and rapamycin produced a synergistic inhibitory effect on cell growth.

分子量
435.93

可溶性
Soluble in water (partly miscible), DMF, DMSO, ethanol, and methanol.

应用
实验应用
A labeled form of Erlontinib HCl, a potent EGFR autophosphorylation inhibitior

背景
别名
Tarceva-d3; N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy-d3)-4-quinazolinamine Hydrochloride

分子式
C22H17D6N3O4•HCl

MDL
MFCD09840535

制备和贮存
保存方式
Store at -20° C
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